It is determined that Ca 2+ transfer disorder in rat small and large intestines as well as this cation availability reduction in the bone tissue occurs under the glucocorticoid-induced oxidative stress. The revealed changes in the organs and tissues occur to a great degree under the active oxygen metabolite action.
oxidative stress, active oxygen metabolites, Ca 2+ metabolism, intestine, bone tissue
1. Osteoporoz - social'naya problema XXI veka / L.P. Benevolenskaya [i dr.] // Rus. med. zhurn. - 2007. -T.15. - № 4. - S. 315-318.
2. Bondareva L.A., Nemova N.N., Kyayvyaryaynen E.I. Vnutrikletochnaya Sa2+-zavisimaya proteoliticheskaya sistema zhivotnyh. - M.: Nauka, 2006. - 294 s.
3. Vliyanie dimefosfona i ksidifona na pokazateli perekisnogo okisleniya lipidov i antioksidantnoy sistemy krys, dlitel'no poluchavshih prednizolon / I.H. Valeeva [i dr.] // Eksperimental'naya i klinicheskaya farmakologiya. - 2002. - № 2.
4. Vasil'ev Yu.V. Terapiya i profilaktika eroziy zheludka i dvenadcatiperstnoy kishki, associiruemyh so stressovymi situaciyami // Rus. med. zhurn. - 2010. - T.18. - № 22. - S. 1-4.
5. Vladimirov Yu.A. Kal'cievye nasosy zhivoy kletki/Yu.A. Vladimirov // Sorosovskiy obrazov. zhurn. - 1998. - № 3. - S.20-27.
6. Kazimirko V.K., Kovalenko V.N., Mal'cev V.I. Osteoporoz: patogenez, klinika, profilaktika i lechenie. - Kiev: MORION, 2007. - 160 s.
7. Litvickiy P.F. Patofiziologiya: v 2-h t. - M.: GEOTAR-MED, 2002. - 808 s.
8. Lukanina S.N. Vliyanie antioksidanta tiofana na strukturno-funkcional'nuyu organizaciyu kishech nika krys v usloviyah glyukokortikoidnoy nagruzki // Sib. vestn. s.-h. nauki. - 2010. - № 3. - S. 61-68.
9. Ramazanova L.M., Men'shikova I.A., Kamilov F.H. Narusheniya mineral'noy plotnosti kostnoy tkani u muzhchin - rabotnikov himicheskogo proizvodstva // Vestn. OGU. - 2008. - № 9(91). - S.199-203.
10. Rodionova S.S. Sovremennyy vzglyad na glyukokortikoid-inducirovannyy osteoporoz // Rus. med. zhurn. - 2004. - T.12. - № 24(224). - S.236-240.
11. Vliyanie okislitel'nogo stressa na sostoyanie kostnoy tkani tela pozvonka svin'i / A.V. Saharov [i dr.] // Sib. vestn. s.-h. nauki. - 2007. - № 6. - S. 81-86.
12. Binder H., Murer H. Potassium/proton exchange in brush-border membrane of rat ileum // J. Membr. Biol. -1986. - Vol. 91. - P. 77-84.
13. Bowie A., O'Neill L. Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries // Biochem Pharmacol. - 2000. - Vol. 59. - P. 13-23.
14. Zeiss N.J. The apoptosis-necrosis continuum: insights from genetically altered mice // Vet Pathol. - 2003. -Vol. 40. - P. 481-495.
