The article presents a study of histological and morphometric changes of duodenal ulcers piglets with nonspecific gastroenteritis. Target studies were pigs week pigs of live weight 10-13 kg, aged 35-40 days. To establish the histological and morphometric changes of duodenal ulcer at the microscopic level material was received from displaced killed and dead animals. Stained for histological examination material was hematoxilin prepared according to Erlich and eosin according to van Gieson's method and CHIC- reaction. In histological and histochemical preparations of the twelve duodenal ulcer morphometric study of the mucosa, state of epithelium layer and own plate; the thickness of the mucosa and glands of the depth; the height of surface and glandular epithelial cells and infiltration of their mesepistemum lymphocytes, eosinophilic and neutrophilic granulocytes; the contents of the goblet exocrine, as well as their activity in the epithelial layer; the number of mitoses in the epithelium of the glands and the height of surface and glandular epithelial cell was carried out. The changes of mucosa irritation of the twelve duodenal ulcer patients with gastrointestinal form in the peak of the disease was characterized by increased numbers of goblet exocrine in the surface epithelium and the epithelium of the intestinal glands, the overproduction of mucus monocit, increase in the lamina propria inflammatory cell density infiltration by lymphocytes, neutrophilic and eosinophilic granulocytes and vasodilatation of the microvasculature in the lamina propria.
gastroenteritis, cup-shaped exocrynocytes, inflammatory infiltrate
1. Volkova O.V., Eleckiy Yu.K. Osnovy gistologii i gistologicheskoy tehniki. - 2-e izd. - M.: Medicina, 1982. - 304 s.
2. Klimenko V.V. Primenenie probiotikov v veterinarii // Mat-ly ІІІ-ІѴ Mezhdunar. nauch. seminarov. - M.: EKSPRESS, 2002. - S. 32-34.
3. Lelyak A. Probiotiki i funkcional'noe pitanie // Sovremennye tehnologii vosstanovitel'noy mediciny: mat-ly VI Mezhdunar. konf. - M., 2001. - S. 21-23.
4. Sidorov A.M., Subbotin V.V. Osnovy profilaktiki zheludochno-kishechnyh zabolevaniy novorozhdennyh zhivotnyh // Veterinariya. -1998. - № 1. - S. 37.
5. Shahov A.G. Aktual'nye problemy bolezney molodnyaka v sovremennyh usloviyah // Vet. patologiya. - 2003. - № 2. - S. 6-7.
