THE EFFECT OF VARIOUS DOSES OF IODINATED DRUG €�MONKLAVIT-1€� ON THYROID HORMONE LEVEL IN THE BLOOD OF LACTATING EWES OF WEST-SIBERIAN MEAT BREED
Abstract and keywords
Abstract (English):
Altai Region is the territory scarce on iodine, which is an essential element for the synthesis of thyroid hormones. Yodtironines provide all the vital processes of the body, and also have a great influence on the formation of physiological processes, determine the level of productivity of the animal and its reproductive qualities. In this regard the effect of io- dine-polymer drug ‘Monklovit-1’ on the concentration of thy- roid hormones in lactating ewes of the West Siberian meat breed was studied. The studies were carried out under pro- duction conditions of PF LLC “Mayak” of Rodinsky area ofAltai Region. The analysis of the level of thyroid hormones in the serum of lactating ewes made it possible to establish that after lambing, prior to the administration of the preparation, the average value of T4 level was 93.8 ± 2.23 nmol / l and T3 was 3.67 ± 0.30 nmol / l. The concentration of thyroid hor- mones at the peak of lactation in ewes of experimental groups 1 and 2 was higher than in control animals: thyroxin - by 16.7 and 18.7% (P <0.01), triiodothyronine - by 21.6 and 14 % (P<0.01), respectively. By the final stage of lactation (4 months of lactation) in the blood of ewes of experimental group 2, in comparison with the ewes of experimental group 1, the level of thyroxin and triiodothyronine was higher by 2.4 and 8.8 %, respectively. Thus, the use of the drug in the dose of 1 ml per 1 kg of live weight contributed to the increase in functional activity of thyroid gland within physiological norm and ensured high level of metabolism.

Keywords:
-1», iodine, hormones, thyroxine, triiodothyronine, lactation, ewes, West Siberian meat breed, ‘Monklavit-1’
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