The research objective was the definition of micro- structural signs allowing differentiating intraductal ade- nocarcinoma of mammary gland in cats. The questions of histologic diagnostics of intraductal adenocarcinoma of mammary gland in cats were considered. The re- search was carried out in histologic laboratory of the Department of Anatomy, Pathological Anatomy and Surgery of Institute of Applied Biotechnology and Veter- inary Medicine of Krasnoyarsk State Agrarian University in 2017-2018. Mammary glands of cats selected during the operation for the removal of organ tumors in a veter- inary clinic were investigated. Breast tumor pieces were fixed in formalin, embedded in paraffin, sliced on micro- tome and stained sequentially with a nuclear dye - hematoxylin and then cytoplasmic (acidic) dye - eosin. Among malignant neoplasms detected in cats, breast adenocarcinoma was most often detected - 90 % of cases. Average age of sick cats was 10 years. Whenbreast tumor was detected and the diagnosis of adeno- carcinoma was established, the prognosis of the dis- ease was unfavorable, 70-80 % of cats died within a year from relapses. Adenocarcinoma grows relatively slowly, does not metastasize for a long time, which makes it difficult to diagnose in its early stages. Clinical examination of small pets can reveal seals in the mam- mary glands, the increase in regional lymph nodes, and the violation of integument integrity. At this stage of in- spection the differentiation and resolution of exact diag- nosis is impossible. The localization of tumor process and clinical picture do not allow to establish the genesis of cancer process, therefore - to choose the right treat- ment strategy. The diagnosis of intraductal adenocarci- noma can be made only after histological examination of biopsy or postoperative material. Characteristic micro- structural features for intraductal adenocarcinoma are the proliferation of atypical adenocytes inside the lumen of intralobular and interlobular ducts. Tumor cells are poorly differentiated; the kernels are of different sizes, there are mitotically dividing and necrotized cells.
oncology, mammary gland, histological diagnosis of tumors, adenocarcinoma, cats
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