IMPLICATION OF NEW MEDICINAL COMPOSITION FOR THE TREATMENT OF DYSPEPSIA IN CALVES FROM BLV- INFECTED COWS
Abstract and keywords
Abstract (English):
The aim of the research was to reveal and justi- fy the effectiveness of the developed composition, including ASD 2 fraction, gentamicin sulfate and furazolidone, for the treatment of dyspeptic mani- festations in calves from BLV-infected cows. The objects of the study were newborn calves of Hol- stein and Simmental breeds (1531 heads) from thefarm "Zarya" Tamalinsky district of Penza area. The developed composition was drunk twice a day, in the morning and in the evening, 30 minutes before colostrum getting to stop dyspeptic manifestations in calves, the course lasted 3-5 days. In each group of calves, the General analysis of blood and biochemical parameters of blood was carried out, and also daily weighing of calves was carried out. The use of developed composition allowed to main- tain the average daily weight gain of calves at the level of 630-660 g, to reduce the duration of thera- py in 28.35 % of animals and to increase the safety of livestock to 100 %. In clinical manifestations of dyspepsia in newborn calves, leukocytosis was recorded, morphological picture of the blood of calves in the first day of life was characterized by high content of all shaped elements per unit vol- ume. Glucose levels, the amount of total protein and its fractions were reduced in blood serum, the balance of blood electrolytes was changed. The normalization of physiological parameters of ani- mals’ blood was observed in the dynamics of dys- pepsia treatment.

Keywords:
dyspepsia of calves, bovine leuke- mia, therapy, safety of livestock, increase in body weight, hematological parameters
Text
Text (PDF): Read Download
References

1. Burmenskaya G.A., Vinokurova D.P., Lifencova M.N. Terapevticheskaya effektivnost' preparata «BACELL-M» pri dispepsii telyat // Uchenye zapiski uchrezhdeniya obrazovaniya / Vitebskaya ordena Znak pocheta gosudarstvennaya akademiya veterinarnoy mediciny. - 2016. - T. 52. - № 3. - S. 12-15.

2. Vasil'ev R.O., Troshina T.A. Sravnitel'naya effektivnost' raznyh shem lecheniya dispepsii u telyat // Voprosy normativno- pravovogo regulirovaniya v veterinarii. - 2015. - № 4. - S. 109-114.

3. Gadzaonov R.H., Puhaeva I.V., Hekilaev Dz.Yu. Ispol'zovanie probiotika v profilaktike dispepsii u novorozhdennyh telyat // Izvestiya Gorskogo gosudarstvennogo agrarnogo universiteta. - 2015. - № 52 (ch.4). - S. 168-172.

4. Ismagilova A.F., Chudov I.V. Terapevticheskaya effektivnost' primeneniya kompozicii MEK+A+P pri lechenii toksicheskoy dispepsii u telyat // Problemy veterinarnoy sanitarii, gigieny i ekologii. - 2014. - № 2 (12). - S. 80-86.

5. Lashin A.P., Simonova N.V., Simonova N.P. Fitoprofilaktika dispepsii u novorozhdennyh telyat // Vestnik KrasGAU. - 2015. - № 9 (108). - S. 189-192.

6. Lekarstvennaya kompoziciya i sposob ee primeneniya dlya profilaktiki i terapii dispepsicheskih sostoyaniy novorozhdennyh telyat, poluchennyh ot inficirovannyh leykozom korov: pat. 2646831. Ros. Fede- raciya: MPK A61K 35/00 A61K 31/00

7. Mager S.N. Biologicheskaya harakteristika potomstva zdorovyh i bol'nyh leykozom korov i associativnoe razvitie leykoza i tuberkuleza u zhivotnyh: avtoref. dis. … d-ra biol. nauk. - Novosibirsk, 2006. - 42 s

8. Medvedeva M.A. Klinicheskaya veterinarnaya laboratornaya diagnostika: sprav. dlya ve- terinarnyh vrachey. - M.: Akvapiym, 2009. - 416 c

9. Mosolkov A.E. Zavisimost' nekotoryh morfologicheskih pokazateley krovi bol'nyh dispepsiey telyat ot urovnya vitaminov A i E v krovi stel'nyh korov s uchetom sezonov goda // Vestnik AltGAU. - 2004. - № 2 (14). - S. 61-62.

10. Ob epizooticheskoy situacii po ryadu zaraznyh i osobo opasnyh bolezney zhivotnyh v Rossiyskoy Federacii, avgust 2017 g. / Departament veterinarii Minsel'hoza RF. - URL: http://depvet.samregion.ru/assets/ files/doklad.pdf.

11. Elenshleger A.A., Politova E.O. Ocenka opredeleniya koefficienta katabolizma u novorozhdennyh telyat, bol'nyh dispepsiey // Vestnik Altayskogo gosudarstvennogo agrarnogo universiteta. - 2014. - № 4 (114). - S. 114-119.

12. Polat M., Takeshima S.N., Aida Y. Epidemiology and genetic diversity of bovine leukemia virus // Virol J. - 2017. - № 14(1). - R. 209.

13. The study of the structural features of the lym- phocytes from cattle with and without retroviral infection using atomic force microscopy / D.A. Artemev, E.S. Krasnikova, A.V. Krasnikov [et al.] // Progress in Biomedical Optics and Imaging - Proceedings of SPIE 5, Optical Technologies in Biophysics and Medicine. - 2018.


Login or Create
* Forgot password?