Kazan', Kazan, Russian Federation
employee from 01.01.2007 to 01.01.2025
Kazan, Kazan, Russian Federation
Russian Federation
employee from 01.01.2002 to 01.01.2025
VAK Russia 4.1.2
VAK Russia 4.1.3
VAK Russia 4.1.4
VAK Russia 4.1.5
VAK Russia 4.2.1
VAK Russia 4.2.2
VAK Russia 4.2.3
VAK Russia 4.2.4
VAK Russia 4.2.5
VAK Russia 4.3.3
VAK Russia 4.3.5
UDC 619
UDC 614.31
UDC 636.52
UDC 636.58
UDC 637.54
The objective of the study is to determine the effectiveness of preventive complexes in reducing the harmful effects of mycotoxins in a mixture (aflatoxin B1, zearalenone, and T-2 toxin) on the animal body and in ensuring the safety of meat products for consumers. The objects of the study were mycotoxins, 80 chinchilla rabbits, and preventive complexes (PC). To reproduce mycotoxicosis, the trichothecene toxin T-2 (1.2 mg/kg), the hepatocarcinogen aflatoxin B1 (0.3 mg/kg), and the estrogenic mycotoxin zearalenone (1.7 mg/kg) were selected. The organoleptic, physicochemical, and microbiological parameters of rabbit meat were assessed in accordance with the requirements of the current regulatory documentation. Residual amounts of mycotoxins in meat and liver samples were determined chromatographically. Organoleptic assessment of meat from the toxic control group revealed deviations from the standard parameters, indicating questionable freshness. Meat from rabbits treated with prophylactic complexes (with and without mycotoxin administration) met established quality and freshness standards. In toxicology control meat samples, an increase in volatile fatty acid content to 3.12 mg KOH (meat of questionable freshness) was recorded. Pre-slaughter live weight and fresh carcass weight of rabbits in the toxic control group were lower than those in the biological control group by 10.26 % (p < 0.001) and 18.03 % (p < 0.001). Slaughter yield was 8.68 % lower in the toxic control group than in the biological control group (p < 0.01). In a comparison between the complexes, complex PK3 had higher slaughter yield values. Aflatoxin B1, zearalenone, and T-2 toxin were detected only in the meat and liver of rabbits in the toxic control group. The studied prophylactic complexes had a positive effect on the quality and safety of rabbit meat, indicating the effectiveness of the studied formulations.
mycotoxins, rabbits, meat safety prevention, rabbit meat, rabbit meat quality, meat safety
1. Niaz W, Iqbal S, Ahmad K, et al. Mycotoxins: A comprehensive review of its global trends in major cereals, advancements in chromatographic detections and future prospectives. Food Chem X. 2025;27:102350. DOI:https://doi.org/10.1016/j.fochx.2025.102350.
2. Cao W, Yu P, Yang K, et al. Aflatoxin B1: metabolism, toxicology, and its involvement in oxidative stress and cancer development. Toxicol Mech Methods. 2022;32(6):395-419. DOI:https://doi.org/10.1080/15376516.2021.2021339.
3. Yu J, Pedroso I. Mycotoxins in Cereal-Based Products and Their Impacts on the Health of Humans, Livestock Animals and Pets. Toxins (Basel). 2023;28(15):480. DOI:https://doi.org/10.3390/toxins15080480.
4. Rogowska A, Pomastowski P, Sagandykova G, et al. Zearalenone and its metabolites: Effect on human health, metabolism and neutralisation methods. Toxicon. 2019;162:46-56. DOI:https://doi.org/10.1016/J.TOXICON.2019.03.004.
5. Ropejko K, Twarużek M. Zearalenone and its metabolites-General overview, occurrence, and toxicity. Toxins. 2021;13(1). DOI:https://doi.org/10.3390/TOXINS13010035.
6. Mahmoud A, Escrivá L, Rodríguez-Carrasco Y, et al. Determination of trichothecenes in chicken liver using gas chromatography coupled with triple-quadrupole mass spectrometry. LWT. 2018;93:237-242. DOI:https://doi.org/10.1016/j.lwt.2018.03.043.
7. Tarasova EYu, Kashevarov GS, Saitov VR, et al. Evaluation of objective morphological features of rat hepatocyte mitochondria with combined mycotoxicosis on the background of preventive complexes use. Bulletin of KSAU. 2022,12(189):98-105. (In Russ.). DOI:https://doi.org/10.36718/1819-4036-2022-12-98-105.
8. Mishina NN, Semenov EI., Malanev AV. et al. Veterinary and sanitary examination of broiler chicken meat when using a four-component sorbent in feed against the background of mycotoxicosis. Russian Journal of Problems of Veterinary Sanitation, Hygiene and Ecology. 2023,2(46):174-179. (In Russ.). DOI:https://doi.org/10.36871/vet.san.hyg.ecol.202302007.
9. Ermolaeva OK., Tanaseva SA., Matrosova LE, et al. Quality of Pork Meat in Mycotoxicosis Against the Background of Enterosorbent Use. The Veterinarian. 2020,4:15-20. (In Russ.). DOI:https://doi.org/10.33632/1998-698X.2020-4-15-20.2020.
10. Lešić T, Pleadin J, Kudumija N, et al. Mycotoxin Residues in Chicken Breast Muscle and Liver. Foods. 2025,14(12):2017. DOI:https://doi.org/10.3390/foods14122017.
11. Mafe A, Büsselberg D. Mycotoxins in Food: Cancer Risks and Strategies for Control. Foods. 2024;31{13):3502. DOI:https://doi.org/10.3390/foods13213502.
12. Andrade M, Delgado J, Rodríguez M, et al. Mycotoxins in meat products. Meat Sci. 2025;227:109850. DOI:https://doi.org/10.1016/j.meatsci.2025.109850.



